This big issues are overlap, which has been well addressed, and u joint angle.
This chart describes how quickly the life of the joint is shortened by increasing the angle the joint operates at.
Increasing the angle also causes the shaft to not operate smoothly inducing vibration.
Unlike the constant velocity joints used on all front wheel drive cars and now many all wheel drive ones as well, the rotational angles of the cardan style joints are not uniform throughout 360 degrees.
Yes if you turn one end of the shaft a full turn the other end will also turn a full turn but in between the full 360 degrees the amount of rotation is not always the same at each end. If you take a socket universal joint and try and turn a nut while the joint is at a strong angle you will feel the lumpy action I am referring to.
This link is to a government web site explaining to farmers the limitations of cardan joints
http://www1.agric.gov.ab.ca/$department/deptdocs.nsf/all/eng9924
Dave M7040
Sorry but I dont know why the link is not a link but you can copy and paste into your browser to read it