I would definitely do a 10 Hr break in oil change on a new engine, even one with a filter. I changed out the oil in my new engine at 7 hrs, and even with a large filter when I put some of the drained oil into a clean container, it did not appear to be as clean as I would have thought. It's just a good idea.
Synthetic or not with a new engine should not matter, but synthetic oil should NOT be used to extend change intervals. (Take this from my 10 yrs experience in the trucking industry.) I do not recommend using synthetic oil in the older engines, as it is more leak prone than regular dinosaur oil, and can make small leaks big, and start new ones.
-fordlords-