Ductless one heat pump is Mitsubishi. It's, of course by far, the most quiet inside and out. Best thing about them is there's no heat coil backup needed. More efficient, too. Downside is the refrigerant lines running to all the users. If you put them in from new, these would be so easy to hide.
Mitsubishi offers 3 lines for residential (single zone), each with a different up front cost, and each with different heating performances at various outdoor temps.
For multi zone, their standard 4 zone 3 ton multi zone will only give you around 24,000 BTU/h of heat at 17 degree outside air temp. Their high performance model will give you over 40,000 BTU/h of heat, but you'll need to run a branch box and the cost is substantially higher.
If you do not have supplimental heat, you need to ensure you know exactly what you're getting performance wise for heating capability and at what outdoor temp.
I'd put a single zone in my home if needed, but anything over 2 zones (2 indoor heads) for various reasons, I'd stick to a conventional ducted system if you already have the ductwork and it's just a retrofit job.
If you do put in a high quantity (over 3 indoor heads) multi zone mini split, highly suggest spending the money and put refrigeration ball valves on every liquid and suction line off the indoor head. If one head goes out, without ball valves in place, the whole system is down for repairs.
3 brands of mini splits (over 80 different names being sold in the US and none are made in the US). Go with a very cheap China brand, good expectation you won't be able to get a replacement past 5 years.