I use a MaxBrake brake controller. It requires no setup other than the initial calibration and that is done without a trailer. It has a "gain" that is not really a gain control. It only controls "when" the trailer brakes come on. I have mine set to apply the trailer brakes just slightly before the truck brakes take hold. It works, with out adjustment, whether the trailer is empty or loaded. It is controlled by a pressure sender that is placed inline at the brake master cylinder. I got rid of several controllers because I got tired of having to adjust the controller every time I loaded or emptied my trailer. the newer trucks with the towing packages are equipped with the same type controller. the pro's, all of the aforementioned. Con's Expensive.