Definitely a 7.3 over the 6.0. The 7.3 is the best diesel Ford ever put in a pickup. It's very reliable, fairly easy to work on, and they have decent fuel mileage. While some people have had good experiences with the 6.0, those experiences are hit and miss. The majority of the engines were horrible. Timing chains shredding plugging the oil coolers or going back into the oil pan, the turbos blew up from no waste gate, the head gasket are prone to failure because the EGR plugs and causes the coolant to boil over...I could go on even more but you get the picture. Stay away.
The new Powerstroke is the 6.7, which was just released this year. So far it's proving to be like the 7.3 was. It's the most powerful diesel on the market at the moment and it gets great fuel mileage like most of the previous pre-emissions compliant diesels. I wouldn't hesitate to buy one.