I just did a trip to Cincy last week in my father's Super Crew Eco Boost 4x4 and 3.73 gears. Me, wife, father, 2 kids, and the bed full of baby items to give to a friend.
Left Muncie on 35 to Richmond, your neck of the woods, to I70 then down through Eaton to Fairfield right by Bass Pro and back. We did 23.7 mpg.
His truck, a 2011 has averaged 18.2 mpg since new with some light towing. Its rated at 16/21 window sticker but Motor Trend is getting what he does in their tester on the long term report.
2012 Ford F-150 Lariat 4x4 EcoBoost Long-Term Update 1 - Motor Trend
Chris
I can 19.2 MPG with a 5.0 Screw 4x4 and 3.73's. I could do better but the hills here hurt it. I think it may do 21 on the interstate.
That motor trend test was BS. Everyone I know with a Ecoboost is 18MPG.
I'm sure they can get that.
Most people do not, however. The fleet average on fueleconomy.gov is between 12 and 19.
In a head to head comparison done recently the GM 5.3. beat the EcoBoost in fuel economy. That was a skewed test though.
Car and Driver is really bad about that. They are pro GM.