What's more important is whether you will be driving implements from the drawbar and turning/cornering with them. If not, all that's important is that the pto shaft be parallel in all planes with the implements fixed input shaft (the gearbox input, etc.) If the implement is trailered from the drawbar, then you need to arrange the pto shaft such that the center is right over the hitch pin when the shaft train is straight ahead. This insures a constant velocity driveshaft up to the fixed, driven shaft with a double Cardan shaft. If the rotary load is light, it all won't make a heap of difference. If the load is heavy (as in driving a large pto generator or a hay baler) and you turn, the shaft will go into a wobble mode and the driven gearbox will complain. Other than that, just make sure you have enough room between the pto and the implement to safely hook things up. This also demands you use common shaft lengths to the implement ("36 or 48" is common. I have a 24" on my 9' mower and its difficult). They extend quite a bit, but the more they extend, the more compliant and weak they become. If you twist one, you won't be able to collapse it to unhook.