Space would be the first thing to look at. You have to pull off the exhaust, and all oil and cooling lines. I agree, seems like a lot of work and lots of research, custom brackets maybe, charge air tubes, etc.
If it is a mechanical unit, mucking with the timing may require injector pump work. In my boat, the pump can be rotated a bit which I believe changes the timing a bit. I never mess with it as I have the pump tweaked by a local rebuilder that does all the flow tests and injector pop tests. But that sounds like a way easier option.