As far as limping off the road with one flat on duals, that would be illegal. Will you get a ticket? Probably not.
Super singles are primarily for weight savings. An average triaxle dump can save as much as 3200lbs by switching to singles. As far as gas mileage, they do improve mileage 5-8%, but other tires are available for duals that average similar results.
Fed-Ex recently took delivery of new converter dollies for use in their freight division equipped with super singles. Goodyear supposedly is warrantying the tires for 1 million miles with road service included.
Time will tell if Super singles become the norm, One disadvantage is the track of the unit is narrowed with the singles.