Connect a light bulb to the fuse contacts. When you turn on the key, the bulb will turn on.
Rule out the consumers that are easy to get to first, I suppose the fuel pump and cruise control in this case:
Disconnect the wires/connectors at the consumers, one by one, and watch the bulb. If it goes out, you have found the problem.
If nothing happens at the bulb, you need to dig into the wiring:
Locate the wires at the fuse, disconnect one connector and watch the bulb. If the bulb is still on after a disconnection, leave that connection open and disconnect a connection on another wire and repeat until the bulb goes out.
If the bulb goes out, you know that you have a problem down that line. Reconnect this connector and keep disconnecting/reconnecting down the line in question to find the short circuit. When you have found it, let this part be disconnected and reconnect the connectors that you have left open at the fuse box. Watch the bulb as you do this to make sure that there is not another short circuit somewhere in the other lines.
Now you have isolated the problem and can replace the fuse, the other parts of the system will work while you fix the problem.
Use enough long wires for the bulb, so you can place it were it can be seen when you are doing the testing.