I don't want to give the wrong idea. Differential wear is what is possible with different size tires, but that doesn't mean it has happened. I still think that the odd tires say more about the previous owner than the tractor. And then there's this: I can't think of the last ime I've ever heard of a tractor having a problem with the rear end - regardless of abuse. If it drives around in a tight circle without clanking noises and you can use the wheel brakes without it complaining too much I don't think I'd worry about the rear end. I'd check it with those tests, but expect it to pass.
On used tractors, the first thing that comes up for maintenance is filters and fluids, followed by starter and battery - maybe alternator. After that come hoses for both hydraulic and water. Clean out the fuel tank of course or put on an extra filter in line there. For 4wd, the first mechanical maintenance item is likely to be the front drive shaft U joints followed by the front axle seals. Power brake cylinder seals leaking used to be a weakness of Zetor; I wonder if they fixed that? As you can see from the list, none of this is fatal.... just normal routine upkeep for a tractor that is basically designed with a motor and running gear that will last a lifetime. Motors, transmission, and clutch.... if they operate without bad noises, they will probably operate just the same for a long time.
And check the PTO. People do tend to beat up PTOs.... So check that out for sure. The best tractors have an independent engagement and a PTO clutch back by the PTO shaft. Both are operator activated & entirely separated from the main transmission clutch. That's for taking up the the load gradually instead of just slamming into it.
PTO's also have either an external or internal over-running one-way automatic clutch. In some Ag tractors, the entire PTO - including both PTO clutches - is accessible at the rear of the tractor in case it needs service. European tractors traditionally use the PTO a lot, so their tendency has been to make it easily serviceable but check that out. Of course best news would be that the PTO works normally. Most do. They tend to last as long as the rest of the tractor.
I was surprised when Zetors didn't become more popular in the US. They certainly are popular in a lot of the rest of the world.
Back when Zetor was on the short list of tractors I was looking at, what impressed me was how rugged they were. That in addition to their simplicity. And the ones with the cab were really nice. I'm not a cab guy, but they do have a very nice cab. Shows a lot of thought. In fact, their whole basic design shows thought.
rScotty