ponytug
Super Member
Well, at least wear padded gloves, and take breaks.
Dupuytren's, its related disease in feet, Ledderhose's, knuckle pads, Peyronie disease, are all related to disordered collagen being deposited by cells (fibromyocytes) in response to physical stress, such as vibration, constant holding such as griping handlebar on a bike or steering wheels, or other tools, rubbing, or cold, or even heightened immune response (inflammation) to other things. While there are treatments, none of the current ones are curative, so be careful if there is a family history of the diseases, which may be related. It is genetic, plus other factors like exposure to gripping or vibration work, but the factors are not fully known at the moment.
And, yes two parents without it can have kids who all have it. The genetics of the diseases are really weird, like belts in Belted Galloways.
All the best,
Peter
Dupuytren's, its related disease in feet, Ledderhose's, knuckle pads, Peyronie disease, are all related to disordered collagen being deposited by cells (fibromyocytes) in response to physical stress, such as vibration, constant holding such as griping handlebar on a bike or steering wheels, or other tools, rubbing, or cold, or even heightened immune response (inflammation) to other things. While there are treatments, none of the current ones are curative, so be careful if there is a family history of the diseases, which may be related. It is genetic, plus other factors like exposure to gripping or vibration work, but the factors are not fully known at the moment.
Ledderhose - Dupuytren Research Group
DUPUYTREN LITERATURE: LEDDERHOSE These materials are available for nonprofit educational use. This repository is allowed by copyright disclaimer under title 17, Appendix E, section 107 of the United States Copyright Act. Under this statute, allowance is made for “fair use” for purposes such as...
dupuytrens.org
And, yes two parents without it can have kids who all have it. The genetics of the diseases are really weird, like belts in Belted Galloways.
All the best,
Peter