Might help if the OP said what profile of metal he's considering. I assumed by 'roof metal on a house' he meant corrugated. (He also said standing seam was too expensive).
The profile I'm considering is the 38" wide (36" coverage) 5 rib style. Ribs are 1.25" high.
I think the main problem with through fastener metal panels is the expansion/contraction of the metal due to temperature changes. I read where the length of a 40' metal roofing panel was measured at 20 degrees and again at 100 degrees. It was stated that it expanded 5/8" longer. For a 16' length (which is what I need) that would equate to 1/4". And that's with an 80 degree temperature change. (I can imagine that the temperature of the metal with the summer sun beating down on it versus it's nighttime temperature could be even a greater span, thus you would have at least a daily cycle of expansion/contraction.)
Well, with that degree of expansion/contraction, something has to give. I think it is definitely going to be pushing back and forth on the screws and over a several year period of time, it will no doubt loosen some of the screws. When that happens, I believe I would rather any loose screws be on the ribs rather than on the flats where water would certainly pour in.
Right now, I'm considering the following two options:
1) Bite the bullet and go for standing seam roofing (26ga). The cost for my roof (panels only) would be $2310.
2) Go for the through fastener panels, and get them in 8' & 8'6" lengths. This would probably reduce the thermal expansion problem and would also make it easier for me to handle (I'll have no help on the installation).
The cost of this roof (panels only, 29ga) would be $1224. ($1388 for 26ga)
With these panels, I'll fasten them closely spaced on the flats around the perimeter of the roof (where any leaks would just be through the overhang), and on the roof proper, I'll fasten them on the ribs, but only the outer, overlapping ribs. And instead of #10 screws that are usually used, I think that I would use #14 screws to get a better 'bite' in the wood. (long #14 gasketed screws are available)