Hydroxychloroquine (Plaquenil)
Hydroxychloroquine (Plaquenil) use in the USA must vary from region to region. Locally if you show up at the ER with major COVID-19 symptoms and you are admitted Plaquenil would be drug of choice for otherwise healthy persons since it has a long history of relative safe usage as an antiviral world wide and COVID-19 is caused by a virus.
I think most of us here realize in the next 30-90 days we or someone that we know may likely die from COVID-19 side effects. We also know that most likely none of us or our friends will die from the use of Plaquenil (Hydroxychloroquine) in the next 30-90 days so why fiddle when Rome is burning. Farmers tend to be more practical people so when a relative safe drug like Plaquenil is in our hand and we clearly show signs of this virus we will use it due to its known risk/reward ratio.
We all like a lots of big studies where n=100,000 (the number of people in the study) but at the end of the day our n=1 usage experience is all that counts in our own life.
Plaquenil is an Rx drug so there is always a doctor/pharmacist/other healthcare professional in the picture because the most safe drug can have serious side effects for some. While we may not understand the mechanism of action it does seem to have anti inflammatory effect hence why it can be used for arthritis and other cases of cytokine storm action with varying degrees of success. Most 60-100 year old people have a touch or more of arthritis.