First, it's a huge mistake to assume that radiant systems are automatically effective. I see cases all the time where people made that assumption and now are looking for fixes to make their ineffective system effective. There aren't easy fixes, it's much better to design a system from the get-go to be effective.
The key to a heated floor being effective is for it to provide enough heat to match the heat loss of the room that it's in and keep the room comfortable. The heat loss of the room is determined by the construction of the room and the climate. This can easily vary by a factor of ten, there are no useful rules of thumb and be suspicious of anyone who wants to design using rules of thumb rather than measuring the room, analyzing its construction and looking at climate data.
The amount of heat that a floor puts into a room is entirely determined by the difference between the surface temperature of the floor and the air temperature of the room. There are two common extremes that lead to dissatisfaction with the comfort. The first is if the heating load is so high that in order to meet the heating load the floor has to be so hot that it is uncomfortable to stand on. This problem will be exacerbated if the floor is made from a material that doesn't conduct heat well, because then the floor will have hot and cold spots. The hot spots will be uncomfortably hot and the cold spots won't be putting out any heat.
The other issue is less serious, it happens when the heating load for the room is so low that the surface temperature of the floor has to be so low that it is not perceptibly warm. In the past 20 years or so there has been a dramatic improvement in what is considered acceptably insulated and air-sealed in residential construction, new houses built to the latest standards use a lot less energy to heat than in the past, and this situation is not uncommon in new construction.
Since the floor temperature controls the heat output, you want the floor temperature to be able to change as quickly as the heat load changes. If you have a room with a lot of solar exposure the load can drop precipitously when the sun comes out, and fall just as quickly when it goes away. A floor with low heat capacity will give better comfort.
Concrete conducts heat well, but has fairly high heat capacity. A system like Warmboard combines a layer of high conductivity aluminum with lower heat capacity, to give even heating and better responsiveness. (I'm not specifically promoting Warmboard, it's just the best known brand.)