agree with previous posts. would think your biggest challenges would be predators, watering, soil.
would suggest electric fencing to keep out most deer, squirrels, etc. you will probably have to put up netting during fruiting to keep out birds, but you want to let the pollinators in during flowering in the early spring.
blueberries are most desireable when organic. elemental sulfur is registered organic and is effective in lowering soil pH gradually. be sure to incorporate into soil along with lots of compost and organic matter to keep drainage good.
bberries are shallow rooted so watering is important - daily during high draught and heat conditions. mulch the plants well and keep trees away from the field so there is no root competition.
storage of just picked berries can be an issue. they do freeze well, but aren't as valuable as fresh. the organic label will help here, too. harvesting when perfectly ripe is critical as slightly over-ripe berries are easily damaged.
lastly, be sure to choose a variety good for your zone. as mentioned, the extension office or experience of others in your area will help here. hard frosts at the wrong time aren't your friend. site location also plays a role. if possible, plant the field on a gradual slope so cold air can "drain" away.
good luck!
amp