We've had Volvos, Saabs and Toyotas, and yes, the safety ratings are very high. And, we've had pickups and SUV's. But, to my way of thinking, trucks and SUV's are no more safe than the little cars. The most recent accident I saw was an Expedition that had been run over by a dump truck; I've also seen other SUV's that have been T-Boned by semi's. You can't get a passenger vehicle that's big enough to be king of the road.
Frankly, if one is any kind of a driver, I'd have to say that the smaller and more nimble the car, the safer it is. First, it presents a smaller target, so it's less likely to get hit. Second, because of superior braking and cornering, it's easier to avoid an accident. How many SUV's have rolled over because they can't execute an evasion manuever? There's a reason why some of the ads for cars like Volvos and BMWs show cars evading accidents.
I grant you, that if you DO get nailed by something bigger than you are, you probably don't have much of a chance. But the point I was making in the first paragraph is that the same thing is true even if you're driving a big pickup or SUV. I like my chances in the smaller car. The car I felt safest in was my son's '85 MR2 (which he still has and drives occasionally). If I had to pick one today, it would be the MINI.
I also grant you that if one doesn't have a clue how to drive well, the most nimble car in the world wouldn't help. One of the best ways to learn what a car can, and can't, do, is to try an autocross -- a skill event in which one car at a time negotiates a course made of highway cones, as fast as possible against the clock. They're held in large parking lots and airport runways and put on by local sports car clubs of the Sports Car Club of America.