I prefer slabs. Our dream house we built has a colored concrete slab. The slab is our finished floor. From grade to the floor is about 12 inches on the up slope side of the house. The far down slope side is over 5 feet. The fill was 67 stone. NOTHING has moved.
All but one of the houses we and all of my family have lived in for decades have been slab. Never had a problem with the plumbing in a slab. Friends, neighbors all in slabs and never heard of problem. I am sure they exist but they certainly have not affected the neighborhoods we and my extended family have lived in across many states.
The problem with a wood floor over a crawl space or basement is that it is a wood floor.

A coworker had to rip out her bathroom floor in a very new house because the toilet leaked and rotted out the wood. The toilet seal in our city leaked. It was a pain. It was not really a problem since the house was a slab. If it was on a crawl space I am sure I would have had to rip out the floor and insulation and replaced it. If your toilet plugs and floods you get to go deal with the floor issues in the house and in the insulation in the crawlspace/basement. This happened in our city house. I had to clean up the mess but that was all.
Our floor in our country house is colored finished concrete. It was cheap and durable. If we want to put down wood, slate, tile, etc, we can. Plus, you can use the concrete as mass to help heat and cool your house.
We built a passive solar heated house. It works. It was cheap and easy to do. I would work better if we did not want to see our land and put in huge windows, i.e., holes in the walls to get the views.

But we do like the view and opening the windows as much as well can so it all balances out. A passive solar house and a slab are made for each other.
If you are going to build a house you NEED to read this book,
http://www.buildingsciencepress.com/Builders-Guide-to-HotHumid-Climates-P2.aspx.
The author knows his stuff. I read what he had to say on many a builders forums when he was having conversations regarding building techniques, details and materials. Our house is built according to the details in his book. He has various books specific to the climate in different areas of the country. What works in the South will not work well in the North and vice versa.
Get his book. Read it. Also read the information on the Building Science website.
Lstiburek argues for insulated and humidity controlled attics AND crawl spaces. I think he is correct. However, and he will say this, getting his details approved by a building inspector can be interesting.


We did not have to worry about the crawl space since we don't have one. I would have preferred to have treated the attic so that the heat and cold did not get into the space but I did not fight that battle with the inspectors.
One problem with insulating under the roof is the effect of the heat buildup on the roofing material. The life time and installation of the roofing material can be affected. Asphalt shingles can curl and warp if there is insulation under the roof deck. You have to check with the shingle maker to see what they say.
Houses in the south generally do not have basements since we the frost line is not that deep. In my area the frost line is not even 12 inches down. The reason basements are built up north is that they have to dig down so deep for the foundation so they might as well just have a basement. The only non slab house we ever lived in had a basement since we were so far north. The basement had water issues too.
Later,
Dan