100-125 psi for semis? OK, so I was little off

How long does it take to fill up an empty semi tire? Me thinks my air compressor would wilt at the thought.
RayH: I understand your point: do what the factory says. But as I said, Ford spec'd P-series tires, evidently for soft on road ride and mileage. This is a half ton, not 3/4 ton. It's an F150 chassis, shorter but heavier. Curb weight is ~5400 lbs, so with me, a load, full tank, etc, I'm sure it's around 5900 lbs. But that's still only 1475 lbs per tire. At 80 psi, the sidewall says the ProComp All Terrains will hold 3195 lbs. No way should I approach 80 psi with my current loads.
Now, as an LT tire, and especially load range E, it's got a much stiffer sidewall and more tread belts. So I've got to increase the pressure from that of the P series. Thanks John Bud and Bird for reminding me about heat and side wall blowouts. I've never had a heat blow out. I've ran over nails, and had a slow leaking tire come off the rim hitting a snow rut in -30C weather, but never a high speed sidewall blow out, thank the Lord.
Wushaw: the Pro Comp web site doesn't have any chart for varying psi for varying loads. Is this something common in the OTR trucking world?
I've noticed a bit worse mileage on my trip computer since the tire changeover, plus the more rapid deceleration, so I agree 45 psi is too low. That's what got me thinking I needed to request the expertise of my TBN knowledgeable compatriots.
I'll try 60 psi, and see what happens.
I'm getting this vehicle ready for a 7.5hr trip in Sept. Four guys, a full load of gear. Driving to Thompson Manitoba (55.8 deg N latitude) then flying 3.5 hrs in a float plain to a hunting/fishing camp on the border of Nunavut and Manitoba. Caribou hunting. The trip of a lifetime!
Thanks everyone for your help.