I'm not into organic gardening, but I tend to avoid pesticides whenever possible. Actually, the couple years I tried Sevin it didn't seem to have much effect.
I take your point. In a perfect world, we would rotate crops perfectly, use manual labor to destroy insects, pay strict attention to varieties, and a host of other things. But that is not the real world for most of us and not for large scale farming in general. But it should remain aspirational.
And perhaps I was a bit flippant about my earlier post on Sevin. But it has been used for many decades with little harm that I can see. And I do find it to be effective on insects and to encourage chemical thinning of fruit in apple trees.
But we do have to go by rules. For example, no one on this farm may spray anything unless I am satisfied they understand the chemical used, the rates of application, can and do use protective gear, and know basic safety rules.
It's not exactly fly-by-night out here on farms. Chemicals are very expensive - we simply wouldn't use them unless we have to. As to personal and environmental harm, I have to believe in the EPA, FDA, and USDA rules and follow them. Before some anti-government types wade in, I honestly don't think the government is my enemy. The rules on pesticides and herbicides seem sane to me, to keep farmers and consumers alike as safe as possible.
But you do have to follow the rules. Even in your home garden and orchard there are time constraints for re-entry after spraying and for consuming veggies and fruits as well. And for washing produce. Read and heed.
If you follow those instructions, I believe you probably will be quite safe (or else how did we get so many old people on this site, LOL).
I am certainly not against more organic farming where it can work, by the way. More study is needed (funded by the government and not Dow Chemical).
Now if you really want to get concerned, read the label on the fly spray under your kitchen counter, the part about organophosphates. That's close to GB Nerve Agent in military terms...so hold your breath when spraying that cloud around LOL.
Regards, and enjoy an apple (but wash it first).