I've used slime on smaller tires and have always had success with both bead/rim leaks as well as small thorns etc. My DX55 had a low front tire last week, so I jacked it up and applied soapy water to the tire. I found 4 slow leaks in the tread. Not wanting to add that much slime to the larger tire, and wanting a cleaner tire and rim if I wanted to add a tube or patch later, I opted for plugs. I slathered the plug cords heavily with rubber cement and they all worked well. I also found the plugs and cement were half price at Menards compared to a couple auto parts store chains.