Not sure they changed the bed design in 2006, my 2001 has white foam pads in the wheel wells on the bed. They hold moisture and rot it from the inside out. Only way to stop it is to remove these pads. My paint was starting to bubble in 2008 and the truck at that time had about 35K on it. Bad bad design.Keep it clean, in a garage but driven regularly to air out, and your climate are the biggest factors. My 2006 F350 doesn't have a drop of rust but I see them all the time rusting out. Chris