All depends. Does your trailer have the hot water bypass? If so, drain your water storage tank and water heater. Put 2 gallons in your water tank, and use your 12v pump to run glycol to your faucets and toilet. Using the bypass, you don't have to fill your water heater to get it out your hot water faucets. If you don't have a bypass, you'll probably need to put 6 or 7 gallons in. Make sure to hit all your drains too. And be sure to get some through your toilet valve. They are fragile and a little moisture will crack them. If you don't have a bypass, it can be done with less if you have an air compressor, air hose adapter and a hand pump, but if you haven't done it before, this is the safest way.
By the way, TSC has a good price on the antifreeze, $3.28/gallon.