All pressure is, is how much pressure is against each square inch inside your tire. If the tire is empty you will have 10 PSI for every square in pushing against the tire walls from the inside. If the tire is 3/4 full of fluid you will have the same amount against the whole surface. It shouldn't matter. If you run 1/2 the required pressure you may spin the wheel inside the tire or maybe even pop a bead if the pressure drops a little more without your knowledge. That scenario might change if the tire is 95% full of fluid, which it should never be, and then you wouldn't have much give at all because liquid won't compress like air might.