Yes. My current tires are loaded with calcium chloride. I would load the new ones also. As for the plies, These Galaxy 6 ply really don't seem to have that strong of a sidewall to them. I had 6 ply skid steer tires on the front of my 4210 and never had sidewall issues. These Galaxy's seem to slice up pretty easy. i was clearing some brush Saturday and the valve stem broke off the front tire. After replacing the stem, I noticed all kinds of deep cuts in the sidewalls of the front tires. I was only clearing small briar patches. May move up to backhoe or skid steer tires all the way around.