I bet you are one of those guys who ranted about having to spend $8,000 on new batteries for the Prius after a few years. I doesn't happen and they have been out for over a decade. Last I checked no consumer has ever had to buy a battery pack. I assume Toyota covered the few that failed.
lets look at the numbers;
50,000 miles @ 15mpg = 3333 gallons @ $5/gal = $16,667
50,000 miles @ 19mpg = 2632 gallons @ $5/gal = $13,158
I'll risk it for $3,500, especially since they tested the snot out of this engine.
If this was going to be a super low mile vehicle, then no, I wouldn't risk it either. heck, I went out of my way to get a V10 for the farm truck, but it replaced a vehicle that averaged less than 2,000 miles a year.
If I start hearing stories about them munching turbos or what have you down the line, I'd use my fuel savings money to get a new truck sooner than I would otherwise.