When I was getting into hunting, I wanted to improve the accuracy of my rifle, so I hung out with different friends that where into reloading. One was big into target competitions, the others where just guys that liked to go hunting once a year and enjoyed reloading. The biggest thing I learned is that it takes a lot of experimenting, trial and error, to find the ideal load for each rifle. I bought dozens of different brand and sizes of bullets, and probably a dozen different powders, in trying to find the right one for my rifle. Eventually we found a very nice combination that allowed me to shoot half inch groups of five at 100 yards on a good day. Some days I was more steady then others, but I did that a couple of times.
Sadly, when I went out hunting with that ideal bullet combination, I found out that they didn't expand very well and just zipped right through the animals that I shot. This happened with two blacktail deer and two caribou up in Quebec. I recovered all four animals, but realized that accuracy didn't always equate to destruction. So I went back to the reloading table with bullets that had a better reputation of mushrooming and retaining weight. I never found a combination that came anywhere near what I had before, and after reading a magazine article about the quality of premium factory loads, I decided to give them a try.
Eventually I came across Federal Premium ammo that gave me one inch groups with some practice. Not as good as my best days with the ideal loads, but this was with a 165 grain soft tip bullet compared to a 150 grain one. With this Premium factory ammo, I've found the results that I was looking for in taking down game, good accuracy, and best of all, no time spent at the reloading table.
We've done the same thing with my wife's deer rifle and found that Winchester Super X gives her one inch groups at 100 yards. So far, she has shot 3 hogs and 2 whitetails that have all been one shot kills.
If you have the time, or you just enjoy the process, go for it. But if you want to find the ideal round for your rifle, I feel that trying all the different premium ammo's out there is a much better option.