Well my owner's manual for my 2011 Silverado doesn't mention fluid changes in anything but the engine for 100,000 miles.
Question is, you have a sealed system that may acquire some steel shavings from gear engagement. Since steel is heavier than oil they sink to the bottom. No composition or any outside influence to degrade oil like in an internal combustion engine other than heat. Well somewhere around 250F Dino oil starts breaking down. Syn is higher than that.....400F I think is the number. I have used a non-contact infrared meter on my gear housings and never saw one over 150F and don't remember that occurrence.
I will say this: I bought a 65 HP tractor in 2007 and the manual said use THD in the front axle and that is what it came with. In 2016 I bought a small tractor of the same mfgr. On the fill port of the front axle, the one with the dipstick, molded in the orange plug was molded 85w-90 only. That was really interesting because with the 65 HP tractor I was smoothing out a field of hard clay after plowing (breaking a field) with the large, hard clumps of sod with some (about half full) weight in the bucket on the front end in an attempt to smooth out the ride and tore up both front wheel bearings...the big ones where the gears connect.
Now what does that tell you about THD in the front axle......by then it was something I already knew. When I reassembled that front end I put 140 wt gear oil in it and that has been a decade ago and no more problems......