Ground clear

[goeduck]

No way I would put something down so toxic nothing would ever grow there. Think about the side effects as oosik says. As BigGG says... put in concrete.

 

[D&D]

This has probably been asked a bunch, but I've seen so much conflicting information.
I need to clear / sterilize a section of ground. And I mean forever, or as close to it as I can. What is the best method for this.
I've read about the chemicals and it sounds like rm43 gets me maybe ai year, but I need forever. Salt it ? It's not a large area, maybe 500-1000 sq. feet .
Thanks for the help !

Forever is a long time. RM43 is just 43% glyphosphate, you can buy higher strengths cheaper.
Problem is, weeds grow. Asphalt/concrete cracks and weeds pop up. Lay fabric and mulch, weeds pop up. Weed seeds are carried by wind, mower discharge chutes and wildlife. Getting rid of weeds is only done by manually pulling them or chemical treatment every so often.

 

[D&D]

I appreciate the desire to treat once and never deal with weeds again. Both the bark chips and fabric will not last "forever". Maybe your time horizon for treating should be the same as the chips and fabric. My 3.2 oz fabric lasts about 3 years and chips certainly less. While you can replenish the chips easily, new fabric is essentially starting over after removing the old fabric. The pricey geotechnicals last longer but that's not a weed stop fabric. Also, there are several chemicals that give you pre-emergence protection up to a year than can be reapplied over the chip/fabric layer.

Since herbicide rules vary by location, I'm reluctant to recommend something for you. I call "DoMyOwn.com" and talk to their tech specialists. Be very cautious about trees, shrubs and adjoining desirables that send roots into your "dead zone".

A 45-60 mil pond liner probably would last considerably longer.