MGH,
You mentioned Creatherm panels in the basement for hydronic radiant heat. Does that mean you'll be putting down a topping slab over the structural slab? If so, I'm wondering why? Why not put the tubing in the structural slab?
What about the main floor? Radiant there too? And again, if so, how will you do it?. The best way I've found is to staple the tubing directly to the subfloor, double plate all the walls, and pour a thin slab the thickness of the lower plate, typically 1 1/2". This gives you a radiant floor that will accept any flooring material and offers some mass for temperature stability. You can tile directly over it in the bath, or tile the whole house. So, you save money on the installation, you save putting in a tile mortar bed in the bathrooms, you get a stable heated floor everywhere and you can design the heat well because you are not locked into a defined tube spacing of the Creatherm panels.
You also mentioned the hydronic system would be later, but again, why? If you want tile, you'll need the hydronic floors or the tile will be very uncomfortable. I don't get why you would want to deliver the heat with blowing air, instead of with a radiant floor system that you are already planning anyway.
Have you done research to find the long term cost of maintenance and the reliability of GS systems? Maybe some others can chime in here too. I'm not saying one case is indicative, but my neighbor put a system in and it has not been reliable or cheap to operate. In other words, it has not lived up to its promise. If cost is a concern, a few service calls can certainly offset the savings you might get through a lower cost of operation. And each of those calls means a period without heat.
With all systems, you have to look beyond the theoretical efficiency and factor in reliability. This can vary wildly between different manufacturers as new products become available and contractors take them on. Manufacturer's reps, visit contractors and architects to promote new products, that then get spec'd in the plans, but have no track record. In my hydronic heating business I have been burned too many times by the newest, and seemingly greatest new products that did not prove to be reliable. All of those cases cost me dearly in warrantee repairs and somewhat in reputation. Be sure you understand the reliability and parts availability of any complicated system you choose.