I knew a woman who worked in a restaurant, and they never did any maintenance, at least not correctly! So one day she decided to paint the restaurant kitchen ceiling instead of actually cleaning it. So she starts painting right over the grease and the grime, meanwhile her husband is cooking on the giant range right there. The edge of the roller pokes a hole into the ceiling through the sheetrock paper and some wasps/yellowjackets come out of the hole and start flying around. She ends up getting stung, and they believe she's allergic, so they call 911. The paramedics come and they rush her to the hospital by ambulance, somewhere along this, either the medics or the ER staff give her the injection. She then has an extremely bad allergic reaction to the injection, and passes away a couple days later.
The wasps/yellowjackets had found their way in past the exterior siding, and hollowed out an entire floor joist bay for over 5 feet, harvesting the sheetrock gypsum all the way down to the paper backing. The entire 5 foot nest was right up against the paper. They had to shut down the kitchen and the exterminator and contractor had to open up the ceiling to spray all the wasps, and scrape the gigantic nest out. They left it open a few days to get all the stragglers, then started the repairs. It was a huge colony!