I don't mean this to be a dummys guide but not knowing your familiarity with firearms I felt basic was better than assuming knowledge that might not be there.
Personally I prefer #4 buck as my home defense load in a pump action Mossberg 500. I do agree that a revolver is less prone to malfunction however, I believe that someone relatively new to firearms would best be served by buying one firearm and getting highly proficient with it rather than have several firearms and finding themselves confused in a desperate situation. My vote goes to a 4 inch 357 with hollowpoints. For practice I echo the comment that 38 loads are cheap but you need to fire enough 357 loads to know how you will react. Finally, fire a few 357 rounds at an indoor range without hearing protection. The noise might deafen you for a bit. You are going to have to know what you will encounter.
Personally I prefer #4 buck as my home defense load in a pump action Mossberg 500. I do agree that a revolver is less prone to malfunction however, I believe that someone relatively new to firearms would best be served by buying one firearm and getting highly proficient with it rather than have several firearms and finding themselves confused in a desperate situation. My vote goes to a 4 inch 357 with hollowpoints. For practice I echo the comment that 38 loads are cheap but you need to fire enough 357 loads to know how you will react. Finally, fire a few 357 rounds at an indoor range without hearing protection. The noise might deafen you for a bit. You are going to have to know what you will encounter.