One other previous poster touched on insurance issues, so I'll elaborate on my experiences:
I had an 01 GMC 3500 cab & chassis with a dump body. A family friend in the insurance business clued me in to the fact that some (many/most?) insurers require a commercial policy for non-standard body trucks. I checked my insurer and one other, and after specifically asking they verified that I needed a commercial policy for anything other than a pickup body. Dump bodies, homemade flatbeds, etc. required a commercial policy even though I did not use the truck in a commercial capacity. The cost premium was minimal - something like $100-$200 a year different, partly because it was a separate policy and therefore did not get any multi-vehicle discount.
The other thing to note with the commercial policy to note is that my carrier did not extend liability coverage to what you were towing. I had to carry a separate policy for coverage on any trailer I towed - again, cost was minimal - $15 per trailer per year or something like that. My 3/4 ton pickup (with commercial registration and 14k cgvw weight bump) was allowed to carry a conventional policy and therefore extended the vehicle liability to any trailer I towed - even if not mine - for no cost.
This was a decade ago and with only a couple companies polled, so YMMV, but if you harbor any insurance paranoia it would be worth checking these out if you have not previously. if you use your vehicle as a business it should be a moot point because I would assume you already carry commercial policies.