I used the Dow Froth-Pak 600 when I re-insulated a wall in my house in 2010. I had some issues with the foam shrinking and delaminating from the studs. I contacted a Dow engineer and he said I had moisture issues in the wood. Dow sent a rep out to look at project. The house was built in 1983 and the wood was totally dry, moisture levels were well within spec and was not the issue. The engineer then send me a usage/installation manual for the Froth-Pak. One thing that was NOT in the directions than come with the Froth-Pak kit is the fact that if you spray on a layer of foam, you are NOT to spray over it for a minimum of 20 minutes!!! This little tidbit should be in the instructions but it is not. The Froth-Pak tanks must be kept between 70dF and 85dF for proper mixing and cure. I built a box to keep the tanks in and made a spot to install an electric heater to keep the tanks at the proper temp.
I have seen numerous situations where closed cell has shrunk or somehow separated from the substrate. . This was one of the primary reasons we opted for open cell. If and when a home settles, wood moves.. this can and will cause closed cell to crack and allow air infiltration..and thus moist yet..and potentially mold. Open cell has its own challenges. But it does flex and move with a structure. However, should there ever be a leak somewhere..it acts like a sponge and that's another issue all together.