You'll have that 427 sitting up front. With the "tongue heavy" trailer, you might want the engine and front wheels sitting a bit closer to the front trailer axle than the wheels do compared to the back trailer axle. Seems to me I read or saw where those Vette's were pretty close to 50/50 weight distribution. You could check that on one of the Vette web page forums.
the "X" placement of the straps will minimize side to side sway of the car on the trailer.
Be sure to check everything after 10-20 miles, just like when you drove semi's.
When they hook up the trailer, go over everything yourself too. I picked up a concrete buggy a couple days ago; the guy did'nt cross the safety chains. It was not a big deal, but if the trailer had come loose, the tongue would've hit the ground. If you cross the chains, it can act as a cradle for the trailer tongue if it comes off the hitch. Check the lights, and hitch connection, the safety chains, the breakaway wire. Check the tires. If something happens on the road, it is your resposibility as the driver.
Another idea a guy gave me is to use a locking cross pin for you reciever. He swore by it. He had one of the cross pins with the hole in it, and the hairpin retainer that goes through the hole. The hairpin came loose, allowing the crosspin to come loose. His crossed safety chains were all that saved the four horses in his trailer.
Check too to see if the trailer has a breakaway braking system. If the trailer brakes free from your truck, you want it to stop, not pass you.