Yes, depending on what the fill is. With Foam I think there are no bad effects. with CACL very corrosive. Antifreeze, CaCl are harmful to environment if released (read tire puncture). Rimguard is supposed to be non-corrosive and environmentally inert. I haven't been able to find it here in CO but keep looking.
Personally, I am not getting the tires filled at first. This alone is a controversial decision on this forum. I know I don't want CaCl (personal decision not meant to alter anybody's beliefs please leave me be /forums/images/graemlins/tongue.gif) and CaCl is what is available around here. I will look for foam availability in my area because I think it is what I want both because it doesn't leak out and because I have nasty plants that make holes in tires. This is the same reason I hesitate looking to hard for Rimguard. By not having it done at the time of purchase I will probably spend more later but to me it is worth it to get what I want. /forums/images/graemlins/cool.gif
Mike