For radon mitigation, the goal is to create a negative pressure under the slab so that the radon goes up the vent and not into the house. You do not want an external inlet pipe as that would make it harder to depressurize the sub slab space. Once you have the venting in subslab, then you need to determine if you need to put a radon fan in the duct by running a radon test in the basement (or main level if it is slab on grade) and seeing if you have an issue or not. If not, leave it. If so, then add the vent fan. Best to plan for the fan with access and power ahead of time as it is easy then.
For any leaking PVC fitting, the best solution to try is to goop it up again and again with pipe cement. It will seal up after an application or two (or three..).
Pipe dope is the thing to use for any threaded fittings. There are several types that stay flexible but seal a whole lot better than teflon tape. I use Harveys or whatever the local store has.